DEN1CH30 Denamarin for All Dog Sizes

Posted November 20th, 2013 by admin


Denamarin chewable tablets for dogs of all sizes is a nutritional supplement for dogs intended to improve and support liver function.


Denamarin’s active ingredients, SAMe (S-adenosylmethionine) and silybin, enhance liver’s antioxidative and regenerative properties, improve bile flow and aid digestion in dogs and cats. Denamarin also supports brain health in older animals.


Liver is “the chemical factory” of the body; it has the main part in all processes of detoxification in the body and plays an important role in digestion (production of bile), blood clotting and vitamin absorption. If liver function is somehow compromised, due to overload of toxins, the animal’s overall condition will deteriorate, and general health will be jeopardized. There is a large number of diseases and conditions that can stop liver from functioning properly. The symptoms of liver failure usually include vomiting, loss of appetite with weight loss, changes in stool appearance and weakness. Advanced liver disease comes with more specific signs: jaundice, swollen abdomen, confusion and seizures. Laboratory tests upon veterinary examination will show impaired liver function.

 DEN1CH30 Denamarin for All Dog Sizes


Numerous diseases, chemicals, drugs and toxins can damage the liver. There are certain viral, parasitic and bacterial diseases that can directly damage the liver, such as leptospirosis, heartworm infection or infectious canine hepatitis. Metastatic tumors and certain metabolic diseases (Cushing’s syndrome, diabetes mellitus) can also lead to liver failure. Numerous drugs can damage the liver, usually as a result of prolonged use and excessive dosage. Certain chemicals can also lead to liver toxicity, such as iron, arsenic, lead, etc. Plants like ragwort, certain mushrooms and mold contaminating food can also cause liver damage.


There are certain breeds of dogs and cats genetically predisposed to various liver issues. For example, Dobermans, Dalmatians, Samoyeds, Cairn Terriers are more prone to chronic hepatitis. Siamese, Burmese, Abyssinian, oriental shorthair and domestic shorthair cats are genetically predisposed to amyloidosis (protein deposition in liver).


1. Are there any known side effects to Denamarin?

a) There are no known adverse reactions to Denamarin; all of its active ingredients are very well tolerated by dogs and cats.

2. How can I know if Denamarin is working for my pet?

a) Be sure to monitor your changes in your pet’s attitude, activities and appetite. During the regular veterinary checkups, tests will show any significant improvement in your pet’s condition due to Denamarin administration.

3. Is Denamarin safe to be used with other supplements for liver support?

a) Since there are no known interactions of Denamarin with other supplements or drugs it can be safely combined with other supplements, not only for liver support, but other kinds as well.

4. Are there other liver support supplements for pets available on the market?

a) There are over the counter products available in drug stores or pet food stores that provide certain ingredients found in Denamarin. However, amounts of those useful ingredients are not standardized for dogs and cats and such liver support products may not provide sufficient source of these compounds for your pets.

5. How does Denamarin help my pet’s brain health?

a) SAMe, S-adenosylmethionine, is an important protective compound protecting the brain. Denamarin is a reliable source of SAMe for dogs and cats. It has been proven beneficial for brain health, especially in older patients.

6. Is it safe to administer Denamarin with food?

a) It is best to administer Denamarin on an empty stomach, as the presence of food can affect the absorption of SAMe. But if your pet is reluctant to ingest the tablet, it can be given in a small bite of food.


Denamarin increases detoxifying properties of the liver. Its active ingredients, SAMe (S-adenosylmethionine) and silybin work in synergy to help optimize liver’s structural integrity and its numerous functions. S-adenosylmethionine helps in protecting liver cells from damage and destruction, at the same time improving their power or reparation and regeneration. Silybin stimulates the flow of bile through the liver and improves the digestion, as well as liver’s detoxifying properties.


It is best to administer the Denamarin chewable tablets at least 1 hour before a meal . The presence of food can decrease the absorption of SAMe. If the animal is reluctant to ingest the tablet, it can be given in a small portion of food.


If the animal must receive more than one chewable tablet a day, the total number of daily tablets can be divided into two administrations during the day; morning and evening.

Denamarin tablets dosage instructions for dogs of all sizes:

Weight (lbs.)

# of tablets daily

Up to 6


7 to 15


16 to 30


31 to 45

1 1/2

46 to 60


61 to 75

2 1/2

76 to 90


91 to 105

3 1/2

Over 105



Denamarin chewable tablet for dogs of all sizes contains 225 mg of S-adenosylmethionine and 24 mg of silibyn A+B.


This product is for veterinary use only and is available only from your veterinarian.

Keep away from children.


Store in a cool, dry place.

Keep the lid of the bottle tightly secured to ensure freshness.

Tablets are sensitive to heat and moisture and should not be crumbled or split.


Denamarin is the only high quality liver supportive pet supplement on the market and the only one providing optimal levels of both SAMe and silybin for dogs and cats. There are certain over-the-counter products that provide the same active ingredients as Denamarin, but not in same concentrations. They are not as efficient as Denamarin, but they may be somewhat cheaper Denamarin and can appear in different packages.

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